The" French Connection" Redux
Aug 12, 2004 11:14 AM
by Andrew Smith
In the French study, rats poked their pointy noses through holes in their cages to trigger injections of cocaine. They were allowed access to the cocaine for three months, much longer than the 10- to 30-day drug-use studies normally done with animals.
Compulsive drug-seeking even in the face of bad consequences is a measure of human addiction. So the researchers devised ways to measure that in animals: routinely cutting off the drug supply and measuring the rats' persistence at poking the supply trigger anyway, seeing how hard they worked to get the drug and noting whether they gave up when their feet were shocked.
Yours Fraternally,
Andy
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